Histoplasma Antibodies by Immunodiffusion
Also known as: HISTO PPT
Use
The Histoplasma Antibodies by Immunodiffusion test aids in the diagnosis of histoplasmosis. It is not recommended as a standalone test, as it is designed to detect total antibodies against the H and M antigens of Histoplasma capsulatum. For more comprehensive serological testing, combining it with other tests such as Histoplasma Antibodies by Complement Fixation is advisable.
Special Instructions
Parallel testing is preferred and convalescent specimens must be received within 30 days from the acute specimens. Specimens should be marked clearly as 'acute' or 'convalescent' to ensure accurate processing.
Limitations
This test is not recommended as a standalone method for diagnosing histoplasmosis, as it only detects total antibodies against specific antigens (H and M) of Histoplasma capsulatum. A negative result does not exclude the presence of Histoplasma infection; therefore, it is recommended to use this test in conjunction with more comprehensive serologic testing methods.
New York Approved
Methodology
Immunoassay
Biomarkers
LOINC Codes
- 5218-3
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.15 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Mark specimens plainly as 'acute' or 'convalescent.'
Storage Instructions
Refrigerated. Avoid repeated freeze/thaw cycles.
Causes for Rejection
Contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |