Prostatic Acid Phosphatase (PAP) by Immunohistochemistry
Also known as: PAP IHC
Use
The Prostatic Acid Phosphatase (PAP) test by Immunohistochemistry is utilized to detect the presence of the PAP protein in tissue samples. It is significant in the diagnosis and management of prostate cancer, aiding in the identification of primary or metastatic prostatic carcinoma by highlighting cancerous prostatic cells within the examined tissue. The presence and abundance of PAP can provide information on the presence and extent of prostate cancer, guiding clinical treatment decisions.
Special Instructions
Submit an electronic request for the test. If electronic ordering is unavailable, use the ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number for submission. For further technical details or assistance, contact ARUP Client Services.
Limitations
It is important to note that the results of the Prostatic Acid Phosphatase (PAP) by IHC can be affected by the quality and representativeness of the specimen. Non-representative tissue types and depleted specimens can lead to unreliable results. Accurate interpretation requires proper specimen handling and preparation, adhering to provided guidelines, and considering the clinical context and other diagnostic findings.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides.
Storage Instructions
Protect paraffin block and/or slides from excessive heat. Ship in cooled container during summer months.
Causes for Rejection
Non-representative tissue type; Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |