T‑cell Intracytoplasmic Antigen (TIA‑1) by Immunohistochemistry
Also known as: TIA1 IHC
Use
This test performs immunohistochemical staining for T‑cell Intracytoplasmic Antigen‑1 (TIA‑1), a cytotoxic T‑cell marker, to aid in the identification and characterization of T‑cell and NK‑cell neoplasms. It is utilized as a technical stain only and does not include interpretive pathological consultation.
Special Instructions
Submit as a technical 'stain‑and‑return' (technical only) service; electronic ordering is preferred, or use ARUP Immunohistochemistry Stain Form #32978 if electronic ordering is not available. Transport using ARUP tissue transport kit (supply #47808). Protect paraffin block/slides from excessive heat; do not oven bake precut slides.
Limitations
Specimens fixed other than 10% neutral buffered formalin or improperly prepared slides (e.g., oven‑baked) may yield inadequate staining. Specimens must be representative; depleted or non‑representative tissue is unacceptable. Frozen specimens are unacceptable.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Min: 2 slides
Container
Tissue transport kit
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3‑ to 5‑micron thick) positively charged slides in tissue transport kit (ARUP supply #47808). If sending precut slides, do not oven bake.
Storage Instructions
Room temperature or refrigerated; ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non‑representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |