Helper T-Lymphocyte Marker CD4

Also known as: CD4+ Lymphocytes, T4 Helper Cells

Clinical Use

Order Test

Use

Monitor patient's helper/inducer T-cell status

Special Instructions

Not provided.

Limitations

The test provides immunophenotyping by flow cytometry which involves detecting antigenic determinants using antigen-specific monoclonal antibodies labeled with a fluorescent dye. It's a complex technology with potential variations due to specimen handling, processing times, and storage conditions. Specimen integrity is critical for accurate results, and rejection may occur due to issues like hemolysis, clotting, or being older than 48 hours from the time of draw.

Test Details

Methodology

Cell-based / Cytometry (Flow Cytometry)

Biomarkers

CD4+ T-Lymphocytes

Protein

Absolute CD4+

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Percentage of CD4+

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

65758-5 - T-cell CD4 subset pnl Bld

Result Codes

24467-3 - CD3+CD4+ Cells # Bld
8123-2 - CD3+CD4+ Cells NFr Bld
6690-2 - WBC # Bld Auto
789-8 - RBC # Bld Auto
718-7 - Hgb Bld-mCnc
4544-3 - Hct VFr Bld Auto
787-2 - MCV RBC Auto
785-6 - MCH RBC Qn Auto
786-4 - MCHC RBC Auto-EntMCnc
788-0 - Erythrocyte DistWidth Bld Auto
777-3 - Platelet # Bld Auto
770-8 - Neutrophils NFr Bld Auto
736-9 - Lymphocytes NFr Bld Auto
5905-5 - Monocytes NFr Bld Auto
713-8 - Eosinophil NFr Bld Auto
706-2 - Basophils NFr Bld Auto
75652-8 - Imm Lymphs Bld Ql
751-8 - Neutrophils # Bld Auto
731-0 - Lymphocytes # Bld Auto
742-7 - Monocytes # Bld Auto
711-2 - Eosinophil # Bld Auto
704-7 - Basophils # Bld Auto
71695-1 - Imm Granulocytes NFr Bld Auto
53115-2 - Imm Granulocytes # Bld Auto
58413-6 - nRBC Bld Auto-Rto
18314-5 - Morphology Bld-Imp
35332-6 - Neuts Band NFr Bld Auto
28541-1 - Metamyelocytes NFr Bld
26498-6 - Myelocytes NFr Bld
19252-6 - Megakaryocytes NFr Bld
55433-7 - Immature cells NFr Bld

Result Turnaround Time

1-3 days

Specimen

Whole Blood

Volume

Fill tube(s) to capacity

Minimum Volume

Not provided

Container

Lavender-top (EDTA) tube and yellow-top (ACD-A or ACD-B) tube

Collection Instructions

Invert tube 8 to 10 times immediately after collection. To preserve cellular viability, collect specimen so it will arrive in the laboratory within 48 hours of collection. Indicate date and time of venipuncture on the tube(s) and on the test request form.