Casandra
Casandra Test Code QD03191Version 1 (DRAFT)
Performing Lab
Aquaporin‑4 (AQP4) (NMO‑IgG) Antibody with Reflex to Titer, Serum
Also known as: Transverse Myelitis Antibody, AQP4, NMO antibody, Aquaporin, LETM antibody
Clinical Use
Order TestUse
Detection of serum aquaporin‑4 (AQP4) IgG autoantibodies is clinically significant for the diagnosis of neuromyelitis optica spectrum disorders (NMOSD), also known as Devic’s disease. A positive AQP4-IgG result supports differentiation from other demyelinating diseases such as multiple sclerosis. Reflex to titer when positive provides semiquantitative analysis to assist in disease evaluation and monitoring.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
Aquaporin‑4 (AQP4) IgG
ProteinIgG • Other • Binary (Detected / Not Detected)
Titer (if reflexed) • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
Result Turnaround Time
1-6 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided