Aspergillus Antibody Panel, CF and ID, Serum
Use
This assay is used for serologic assessment of exposure to Aspergillus species by detecting Aspergillus-specific antibodies. It includes two methods: complement fixation (CF) to measure total Aspergillus antibody titer, and immunodiffusion (ID), which differentiates antibodies against specific Aspergillus species (flavus, fumigatus, niger). The combined panel aids in diagnosing Aspergillus-related infections or related allergic conditions.
Special Instructions
Not provided.
Limitations
Test limitations include potential false-negative results early in infection or seronegative cases, possible cross-reactivity, and variability in antibody responses between individuals. Interpretation should consider clinical context; negative ID but elevated CF may indicate exposure without active disease. Intra- and inter-laboratory variations may affect titers. Convalescent titers may be needed for interpretation.
Methodology
Immunoassay (Other)
Biomarkers
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Causes for Rejection
Gross hemolysis; grossly lipemic; grossly icteric
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 30 days |