Cardio IQ Lp‑PLA2 Activity
Also known as: CardioIQ®, PAF-AH
Use
Lipoprotein‑associated phospholipase A₂ (Lp‑PLA₂) is an enzyme produced by macrophages and foam cells within the necrotic core of arterial plaque. Measurement of Lp‑PLA₂ activity assesses disease activity within the arterial wall under the calcified cap of the plaque. Elevated Lp‑PLA₂ has been associated with a two‑fold increased risk for developing coronary heart disease (CHD), and indicates a two‑fold risk of a CHD event (myocardial infarction, coronary revascularization, or CHD‑related death) ([questdiagnostics.com](https://www.questdiagnostics.com/healthcare-professionals/about-our-tests/cardiovascular/cvd-test-descriptions?utm_source=openai)).
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Not provided.
Biomarkers
Lp‑PLA2
Protein
Result Turnaround Time
5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Patient Preparation
Fasting preferred, but not required
Other tests from different labs that may be relevant