Celiac Disease Comprehensive Panel with Gliadin Antibody (IgG)

Casandra

Casandra Test Code QD12302Version 1 (DRAFT)

Performing Lab

Lab Quest DiagnosticsLab Test ID 36336

Celiac Disease Comprehensive Panel with Gliadin Antibody (IgG)

Also known as: Deamidated gliadin

Clinical Use

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Use

This comprehensive panel serves as an initial serologic screening tool for celiac disease by detecting immune response markers—specifically tissue transglutaminase IgA (tTG‐IgA) and total immunoglobulin A (IgA). Measuring total IgA helps identify IgA deficiency (~2–3% of celiac patients), which could otherwise lead to false-negative tTG‐IgA results.

Special Instructions

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Limitations

The accuracy of antibody detection depends on the patient’s gluten consumption; a gluten‑free diet at the time of testing may yield false‑negative results. This panel does not provide a definitive diagnosis—abnormal results warrant further diagnostic evaluation.

Test Details

Methodology

Immunoassay (ELISA)

Biomarkers

Tissue Transglutaminase IgA (tTG‑IgA)

Protein

tTG‑IgA • Expression • Quantitative (Continuous) (e.g., copies/mL, % expression)

Total Immunoglobulin A (IgA)

Protein

Total IgA • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Result Turnaround Time

3-5 days

Specimen

Serum

Volume

Not provided

Minimum Volume

Not provided

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