Epidermal Antibodies with Reflex to Titers

Use

The detection of anti‑skin antibodies aids in the diagnosis of chronic vesicular‑bullous diseases including pemphigus, pemphigoid, cicatricial pemphigoid, and epidermolysis bullosa acquisita (EBA). Epithelial intercellular antibodies are diagnostic for pemphigus and occur in over 90% of sera from all active forms. Antibodies to basement membrane antigens of stratified squamous epithelium occur in about 70% of active bullous pemphigoid, 50% of vesicular pemphigoid and EBA, and 10% of cicatricial pemphigoid patients.