Gliadin (Deamidated) Antibody (IgG, IgA)
Also known as: Antigliadin Ab (IgA, IgG), Deamidated Gliadin (IgA, IgG), Anti-Gliadin Ab (IgA
Use
Detection of antibodies to gliadin, one of the major protein components of gluten, is a sensitive assay useful in diagnosing celiac disease. However, gliadin antibodies may be found in individuals without celiac disease; thus gliadin antibody assays are less specific than assays measuring antibodies to endomysium and transglutaminase. Deamidation of gliadin enhances antibody binding, improving diagnostic accuracy compared to standard gliadin antibody assays.
Special Instructions
Not provided.
Limitations
Gliadin antibodies may be found in individuals without celiac disease, reducing specificity compared to assays measuring antibodies to endomysium and transglutaminase. Deamidated gliadin peptide assays have improved accuracy but may still require clinical correlation.
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
Gliadin (Deamidated) Ab (IgA)
ProteinGliadin (Deamidated) Ab (IgG)
Protein
Result Turnaround Time
4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
0.5 mL
Container
Transport tube
Causes for Rejection
Gross hemolysis • Grossly lipemic
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 30 days |
Other tests from different labs that may be relevant