Use

This test is intended for the detection and semi‑quantitation of IgG anti‑prothrombin (aPT) antibodies. Antiphospholipid (aPL) antibodies are a heterogeneous group of antibodies that bind to protein‑phospholipid complexes; aPT antibodies may be detected in patients with autoimmune diseases (e.g., systemic lupus erythematosus) and/or antiphospholipid syndrome (APS). The aPT antibody concentration values obtained from this assay serve as an aid to diagnosis only. If results are negative but clinical history suggests APS, further testing for APS criteria antibodies (IgG and IgM beta‑2‑glycoprotein I, cardiolipin antibodies, lupus anticoagulant) is recommended, with repeat testing in at least 12 weeks to demonstrate persistence of antibodies.