Antiphosphatidylserine/Prothrombin Complex, IgG and IgM
Also known as: Antiphosphatidylserine/Prothrombin Antibody
Use
As an aid in the diagnosis of certain autoimmune thrombotic disorders, such as antiphospholipid syndrome (aPS). Antibodies to PS/PT correlate with the presence of lupus anticoagulants (LA) and this test may be useful in cases with difficult LA test interpretation. This assay may also assist in the determination of risk for thrombosis as well as obstetric complications in patients with antiphospholipid antibodies.
Special Instructions
Inclusion of this test into the standard antiphospholipid antibody panel may allow better quantification of thrombotic risk and risk for pregnancy loss. Testing schedules may vary, and additional time may be needed for confirmatory or reflex tests.
Limitations
The clinical significance of antiphosphatidylserine/prothrombin antibodies outside of antiphospholipid syndrome or systemic lupus erythematosus remains under investigation. Diagnosis cannot be made based solely on laboratory results; results must be interpreted with the patient's clinical condition. Treatment decisions should rely on both clinical and laboratory findings.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 85358-0
- 85359-8
- 85359-8
- 85358-0
Result Turnaround Time
4-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube, gel-barrier tube
Collection Instructions
Separate serum from cells by centrifugation.
Storage Instructions
Freeze
Causes for Rejection
Gross hemolysis; gross lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 6 hours |
| Refrigerated | 6 hours |
| Frozen | 12 months |