TRAb (TSH Receptor Binding Antibody)
Also known as: Thyrotropin Receptor Antibody, TSH Receptor Binding Antibody, Thyrotropin Binding (TBII), TBII
Use
Measurement of TRAb is used to diagnose and manage Graves’ disease, neonatal hypothyroidism, and postpartum thyroid dysfunction. TRAb, which measures the ability of antibodies to inhibit TSH binding to its receptor, reflects the presence of either or both the stimulatory and inhibitory immunoglobulin classes. ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/Medfusion/test/542811?utm_source=openai))
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (ELISA)
Biomarkers
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Serum separator tube or plain red
Collection Instructions
Allow serum to clot at room temperature; separate serum from cells or gel barrier within 1 hour
Causes for Rejection
Gross hemolysis; serum received in a gel barrier tube or on the cells
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 21 days |