Melanoma Antibody, HMB45 by Immunohistochemistry (Red Detection)
Also known as: HMB45R IHC
Use
The Melanoma Antibody, HMB45 by Immunohistochemistry (Red Detection) test is used to detect human melanoma black-45 protein expressed in melanocytic tumors. It serves as a useful marker for the diagnosis and evaluation of melanoma, aiding in the differentiation between melanoma and other tumors. This test helps clinicians identify melanoma cells in tissue samples, thus providing critical information for treatment planning and prognostic assessment.
Special Instructions
Submit electronic request or use ARUP Immunohistochemistry Stain Form if electronic ordering capability is unavailable. Requires ARUP client number for submission.
Limitations
This test is performed as a stain and return (technical) service only. It has not been cleared or approved by the US Food and Drug Administration and is intended solely for clinical purposes within a CLIA certified laboratory. Interpretation of results should consider the clinical and pathological context, as staining patterns may vary across specimen types.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Positively charged slides or tissue block in a tissue transport kit
Collection Instructions
Formalin fix (10 percent neutral buffered formalin); paraffin embed. Transport tissue block or 5 unstained slides (3- to 5-micron thick sections). Available through ARUP eSupply or contact Client Services. Do not oven bake precut slides.
Storage Instructions
Room temperature or refrigerated, ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |