Monoclonal Protein Study, 24 hour, Urine
Also known as: U-PEP
Use
Aids in the diagnosis and monitoring of monoclonal gammopathies using 24-hour urine specimens. This test involves the measurement of monoclonal proteins in urine, which can help detect and monitor conditions such as multiple myeloma and other related plasma cell dyscrasias.
Special Instructions
Collect 24-hour urine with refrigeration during the collection process. Ensure that the total volume and collection time interval are recorded on the transport tube and test request form.
Limitations
Total urine protein measurement using this method characteristically underestimates urinary light chains. Accurate paraprotein excretion calculation may be challenging in cases where the 24-hour urine collection volume is not properly documented.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 49277-7
- 19153-6
- 30211-7
- 42482-0
- 17811-1
- 17813-7
- 17815-2
- 17817-8
- 17819-4
- 42484-6
- 11526-1
- 2888-6
- 2889-4
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
Not provided
Minimum Volume
4 mL
Container
ARUP standard transport tubes
Collection Instructions
Transfer two 4 mL aliquots from well-mixed 24 hour collection to individual ARUP standard transport tubes.
Patient Preparation
Collect 24-hour urine. Refrigerate during collection. Also acceptable: Random urine specimens and urine supernate.
Storage Instructions
Refrigerated.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 1 month |