Special Stain, Fontana-Masson
Also known as: FONTANA SS
Use
The Special Stain, Fontana-Masson is primarily used for the detection of argentaffin substances, such as melanin and other related pigments. It is an important tool in histopathology for identifying conditions characterized by the presence of these pigments. This test is essential for differentiating melanin from other pigments in tissue samples, which is crucial for accurate diagnosis in dermatopathology and other specialized fields of pathology.
Special Instructions
The use of the ARUP Anatomic Pathology Test Request Form (#32960) is recommended for ordering this test. Samples must be prepared in formalin and paraffin embedded for accurate staining. Ensure specimens are not exposed to excessive heat during transportation. Submit electronic requests if possible, or use the ARUP client number to facilitate processing. Contact ARUP Client Services for technical details.
Limitations
This test is primarily a technical service, and results depend on the quality and representativeness of the specimen submitted. Specimens with non-representative tissue types or depleted samples are considered unacceptable and will lead to possible rejection. Accurate interpretation requires consideration of clinical history and other diagnostic tests. The stability of the specimen is indefinitely assured in ambient and refrigerated conditions, but frozen specimens are unacceptable.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 10810-0
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
1 slide
Collection Instructions
Transport tissue block or 2 unstained (3- to 5-micron thick sections), positively charged slides in a tissue transport kit. Specimens should be fixed in 10 percent neutral buffered formalin and embedded in paraffin.
Storage Instructions
Protect paraffin block and slides from excessive heat. Ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with nonrepresentative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |