Oncology FISH Analysis - NHL FISH Panel
Use
Oncology FISH Analysis for non-Hodgkin's Lymphoma is designed to identify chromosomal abnormalities linked to NHL, relevant for diagnostics and prognostics. This test aids in detecting common translocations and rearrangements which are critical for tailoring treatment plans. Given the variable expressions and genetic markers, interpreting results within a full clinical context is crucial. Patients presenting symptoms such as swollen lymph nodes and unexplained fevers may benefit from this analysis, providing insights that could lead to better targeted interventions.
Special Instructions
This test requires the submission of a sample collected in a specific container, with clear labeling and appropriate shipping methods to maintain specimen integrity. Patients should be advised about the importance of timely sample collection and shipping to ensure the test results are reliable and accurate.
Limitations
This assay focuses exclusively on certain loci and may not detect other translocations outside the specified targets. The absence of detected abnormalities does not rule out a diagnosis of lymphoma, as not all genetic changes are captured by this method. Additionally, the sensitivity may vary between patients based on cellularity and other underlying conditions. It’s crucial for healthcare professionals to consider these limitations when utilizing the test results in clinical decision-making.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow (Fresh)
Volume
3-5 cc
Minimum Volume
2 cc
Container
Sodium Heparin tube (Green-Top)
Collection Instructions
Draw bone marrow in a Sodium Heparin (green-top) tube(s).
Storage Instructions
Ship at ambient temperature (18-25°C/64-77°F) in an insulated container by overnight courier.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hrs |