Gluten Sensitivity Antibodies Cascade
Also known as: Nonceliac Gluten Sensitivity
Use
This test is intended to aid in the diagnosis of gluten sensitivity in patients with symptoms suggestive of this condition. It is recommended for children and adults with suspected sensitivity to gluten.
Special Instructions
Not provided.
Limitations
Patients with gluten sensitivity who are on a gluten-free diet may have negative serological test results for gluten sensitivity. Antibodies to deamidated gliadin peptide and tissue transglutaminase are specific to celiac disease while antibodies to native gliadin are present in patients with and without gastrointestinal manifestations and are serological evidence of gluten sensitivity.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 31017-7 - tTG IgA Ser-aCnc
- 58710-5 - Gliadin peptide IgG Ser-aCnc
- 20496-6 - Gliadin IgG Ser IA-aCnc
- 6276-0 - Wheat IgE Qn
Result Turnaround Time
4-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Gel-barrier tube, red-top tube or serum transfer tube
Collection Instructions
Specimen should be free of bacterial contamination, hemolysis and lipemia.
Storage Instructions
Room temperature
Causes for Rejection
Lipemia; hemolysis; microbially contaminated sera
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant