Protein Electrophoresis With Interpretation, 24-Hour Urine With Reflex to IFE, 24-Hour Urine
Also known as: Urine (24-Hour) Interpretation, Protein Electrophoresis and Reflex to IFE, 24-Hour
Use
Work up myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight proteins.
Special Instructions
Not provided.
Limitations
The test may not detect small M-spikes in cases where the concentration is below the sensitivity of the method. Results should be interpreted in conjunction with clinical findings, other laboratory tests, and imaging studies. Reflex testing to immunofixation (IFE) is performed at an additional charge only if an M-spike is detected, which may delay final results.
Methodology
Other
Biomarkers
LOINC Codes
- 2888-6 - Prot Ur-mCnc
- 2889-4 - Prot 24h Ur-mRate
- 13986-5 - Albumin 24h MFr Ur Elph
- 13984-0 - Alpha1 Glob 24h MFr Ur Elph
- 13987-3 - Alpha2 Glob 24h MFr Ur Elph
- 13988-1 - B-Globulin 24h MFr Ur Elph
- 13989-9 - Gamma glob 24h MFr Ur Elph
- 42484-6 - M Protein 24h MFr Ur Elph
- 42482-0 - M Protein 24h Ur Elph-mRate
- 77202-0 - Laboratory comment Report
- 11502-2 - Laboratory report
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
20-mL aliquot
Minimum Volume
11-mL aliquot
Container
12-mL plastic transport tube (Labcorp No. 23597) without preservative
Collection Instructions
Mix well.
Storage Instructions
Refrigerated (preferred) or room temperature
Causes for Rejection
Preservative added
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
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