CD43, IHC with Interpretation
Use
CD43 is a cluster of differentiation antigen expressed on T lymphocytes, myeloid cells (including granulocytes and precursors, monocytes, macrophages, histiocytes), plasma cells, and megakaryocytes; immunohistochemical evaluation with interpretation helps in characterizing hematopoietic and related cell types.
Special Instructions
Interpretation provided by pathologist as part of the test (“with Interpretation”).
Limitations
Use of fixatives other than 10% formalin may compromise staining quality. FFPE slide age, improper fixation or handling can affect immunoreactivity; charged slide storage and surface chemistry are important for consistent staining.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Minimum of 2 unstained slides (5 µm) or tissue block (~0.2 cm × 0.2 cm × 0.2 cm)
Collection Instructions
FFPE tissue block with corresponding H&E and/or unstained 5 µm slides; send all slides within 6 weeks of cutting; mount on poly‑L‑lysine or charged (+) slides, air dry; do not oven dry.
Storage Instructions
Store at room temperature.
Causes for Rejection
Frozen specimens or poorly fixed tissue; slides older than 6 weeks; improper slide mounting (non‑charged) or drying.
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | Unacceptable |