Filaria Antibody (IgG4)
Also known as: Filariasis
Use
This assay detects IgG4 subclass antibodies to filarial parasites, including Dirofilaria immitis, Wuchereria bancrofti, Brugia malayi, and Onchocerca volvulus. Chronic filarial infections manifesting as elephantiasis may not show a significant IgG4 response and cannot be ruled out by this test. Cross-reactivity may occur with antibodies to other nematodes, particularly Strongyloides.
Special Instructions
Specimen collected Wednesday; send to Mayo Medical Laboratories via Quest; set-up Wednesday.
Limitations
Chronic elephantiasis may not result in significant IgG4 antibody response, so infection cannot be ruled out. Cross-reactivity with antibodies to other nematodes (e.g., Strongyloides) may occur. Not FDA cleared or approved; developed and validated under CLIA.
Methodology
Immunoassay
Biomarkers
LOINC Codes
- 14208-3
- 14208-3
Result Turnaround Time
6-20 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
Plastic vial (after centrifuging red‑top or SST tube)
Collection Instructions
Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
Storage Instructions
Refrigerated preferred; ambient or frozen acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 30 days |