Muc-4 by Immunohistochemistry

Casandra

Casandra Test Code AR58725Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2004008CPT Code 88342

Muc-4 by Immunohistochemistry

Also known as: MUC4 IHC

Clinical Use

Order Test

Use

The Muc-4 by Immunohistochemistry test is intended for the staining and analysis of tissue samples to detect the presence of the MUC4 protein. MUC4 is a membrane-associated mucin that is expressed in various epithelial cancers and may be involved in cancer progression and metastasis. This test aids clinicians in identifying MUC4 expression patterns in tissue specimens, providing insights into the diagnosis and potential prognosis of certain cancers. It is specifically used within a clinical context to guide pathology evaluations.

Special Instructions

Not provided.

Limitations

The test has not been cleared or approved by the FDA but is performed in a CLIA certified laboratory intended for clinical purposes. While it provides information on MUC4 protein presence, it does not diagnose cancer nor indicate other conditions independently. The interpretation of results should be conducted by a qualified pathologist within the broader clinical context. Tissue samples must be formalin-fixed and paraffin-embedded; non-representative tissue types and depleted specimens will be rejected.

Test Details

New York Approved

Methodology

Immunoassay (IHC)

Biomarkers

MUC4

Protein

IHC

Expression • Categorical (e.g., Positive / Negative / Indeterminate)

LOINC Codes

Result Codes

94736-6 - Tissue block ID Spec

Result Turnaround Time

1-3 days

Specimen

Tissue (FFPE)

Volume

Not provided

Minimum Volume

2 slides

Container

Tissue transport kit (ARUP supply #47808)

Collection Instructions

Collect tissue or cells. Use formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Protect paraffin block/slides from excessive heat. If sending precut slides, do not oven bake.