SOX-10 By Immunohistochemistry (DAB Detection)
Also known as: SOX10 IHC
Use
The SOX-10 by Immunohistochemistry (DAB Detection) test is used to detect the presence of the SOX-10 protein in tissue samples. This test is specifically employed in the immunohistochemical staining process to aid in the diagnosis of certain types of tumors, particularly those of neural crest origin, such as melanoma and schwannoma. Using an anti-SOX-10 antibody, this test allows pathologists to examine the expression pattern of the SOX-10 protein in cells and can provide valuable information in the diagnosis and differentiation of these tumor types.
Special Instructions
Not provided.
Limitations
The SOX-10 by Immunohistochemistry test is a laboratory-developed test and has not been cleared or approved by the FDA. It is not intended to be the sole evidence for a diagnosis of any disease and should be used in conjunction with other diagnostic tools and clinical assessments. Potential limitations include false negatives or positives due to inadequate specimen integrity or improper handling. Results interpretation must consider these factors, and the quality of the specimen significantly affects the accuracy of the test outcomes.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
SOX-10
Protein
LOINC Codes
- 94736-6 - Tissue block ID Spec
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue block or positively charged slides
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Transport in a tissue transport kit if possible.
Storage Instructions
Protect paraffin block and/or slides from excessive heat.
Causes for Rejection
Specimens with non-representative tissue type or depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
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