Anti-EJ Ab (RDL)
Also known as: Anti-histidyl-tRNA synthetase autoantibodies
Use
Anti-histidyl-tRNA synthetase autoantibodies are the most common Myositis Specific Antibodies (MSA), comprising 30-40% of Idiopathic Inflammatory Myopathies (IIM), although EJ specifically, is seen in less than 5% of IIM. Anti-Synthetase antibodies can be found in polymyositis, dermatomyositis or overlap myositis. Symptoms associated with these antibodies include non-erosive arthritis, ILD, fever, mechanic's hands and Raynaud's.
Special Instructions
Testing schedules may vary. It is recommended to separate serum from cells within one hour of collection and transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration. Grossly hemolyzed, bacterial contamination, lipemic, icteric, and non-serum specimen types are causes for rejection.
Methodology
Other
Biomarkers
LOINC Codes
- 45149-2
- 45149-2
Result Turnaround Time
14-21 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |