Antiphosphatidylserine/Prothrombin Complex, IgM
Also known as: Antiphosphatidylserine/Prothrombin Antibody
Use
As an aid in the diagnosis of certain autoimmune thrombotic disorders, such as antiphospholipid syndrome (aPS). Antibodies to PS/PT correlate with the presence of lupus anticoagulants (LA) and this test may be useful in cases with difficult LA test interpretation. This assay may also assist in the determination of risk for thrombosis as well as obstetric complications in patients with antiphospholipid antibodies.
Special Instructions
Not provided.
Limitations
The clinical significance of aPS/PT antibodies in diseases other than aPS or SLE is under investigation. Diagnosis cannot be made on the basis of aPS/PT antibody results alone and results must be interpreted with the patient's clinical condition. Treatment must not be initiated on the basis of aPS/PT antibody results alone and should also rely on supportive clinical indications. Patients with aPS and be a PS/PT positive yet lupus anticoagulant, anticardiolipin or anti-B2Gp1 negative.
Methodology
Enzyme-linked immunosorbent assay (ELISA)
Biomarkers
LOINC Codes
- 85358-0
- 85358-0
Result Turnaround Time
4-8 days
Related Documents
For more information, please review the documents below
Specimen
Unknown
Volume
Not provided
Minimum Volume
Not provided
Causes for Rejection
Gross hemolysis; gross lipemia