Herpes Simplex Virus 1 (IgG), Type‑Specific Antibody
Use
Type‑specific IgG antibody testing for HSV‑1 (HerpeSelect®) is intended to detect past or recent HSV‑1 infection as an aid in presumptive diagnosis. A positive result suggests exposure and lifelong latent infection; a negative result does not rule out early infection (may need repeat testing after 12 weeks) or infection with strains lacking glycoprotein G (gG). This assay is not preferred for diagnosing acute genital herpes, for which lesion-based NAAT or culture is recommended. The HerpeSelect® assay is type‑specific and helps distinguish between HSV‑1 and HSV‑2 infections.
Special Instructions
Not provided.
Limitations
Serologic testing may yield false‑negative early in infection; seroconversion may take up to 12 weeks—repeat testing recommended if early exposure suspected. False‑negatives may also occur in rare HSV‑2 isolates lacking gG. Serology is not diagnostic of active lesions; NAAT or culture of lesions is preferred for current infection. Routine screening not recommended due to false positive risk.
Methodology
Immunoassay (ELISA)
Biomarkers
Herpes Simplex Virus 1 IgG
Protein
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Container
Serum separator tube (SST)
Collection Instructions
Blood draw; use SST
Patient Preparation
None
Storage Instructions
Unknown
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