Herpes Simplex Virus 1 (IgG), Type‑Specific Antibody
Use
Type‑specific IgG antibody testing for HSV‑1 (HerpeSelect®) is intended to detect past or recent HSV‑1 infection as an aid in presumptive diagnosis. A positive result suggests exposure and lifelong latent infection; a negative result does not rule out early infection (may need repeat testing after 12 weeks) or infection with strains lacking glycoprotein G (gG). This assay is not preferred for diagnosing acute genital herpes, for which lesion-based NAAT or culture is recommended. The HerpeSelect® assay is type‑specific and helps distinguish between HSV‑1 and HSV‑2 infections.
Special Instructions
This test uses the HerpeSelect® type‑specific immunoassay platform. Reflex testing applies only in broader HSV‑1/2 panels (not applicable to this single test code 3636). Order via provider; no at‑home or DTC ordering indicated. No special patient preparation required.
Limitations
Serologic testing may yield false‑negative early in infection; seroconversion may take up to 12 weeks—repeat testing recommended if early exposure suspected. False‑negatives may also occur in rare HSV‑2 isolates lacking gG. Serology is not diagnostic of active lesions; NAAT or culture of lesions is preferred for current infection. Routine screening not recommended due to false positive risk.
Methodology
Immunoassay (ELISA)
Biomarkers
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Container
Serum separator tube (SST)
Collection Instructions
Blood draw; use SST
Patient Preparation
None
Storage Instructions
Unknown