Immune Cell Function Assay (ImmuKnow®)
Use
The ImmuKnow® Immune Cell Function Assay assesses cell‑mediated immunity by measuring ATP production from CD4+ T‑cells following stimulation, and is used particularly in immunosuppressed populations—such as solid‑organ transplant recipients—to aid in evaluating the degree of immune suppression and risk for infection or rejection. Results should be interpreted alongside clinical presentation and history. ([kuhlab.testcatalog.org](https://kuhlab.testcatalog.org/show/IKNOW?utm_source=openai))
Special Instructions
Not provided.
Limitations
Specimens received beyond the 30‑hour stability window, or those that are refrigerated, frozen, clotted, or transferred to other tubes, will be rejected. The assay is qualitative and does not quantify the level of immunosuppression. Results must be correlated with clinical context and other indicators. This test cannot be added onto other specimens. ([kuhlab.testcatalog.org](https://kuhlab.testcatalog.org/show/IKNOW?utm_source=openai))
New York Approved
Methodology
Other
Biomarkers
Result Turnaround Time
36-48 hours
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Not provided
Minimum Volume
0.5 mL
Container
Green top (sodium heparin) tube
Collection Instructions
Send whole blood in original tube; do not refrigerate or freeze; critical ambient; cannot collect after 1300 on Friday or on a weekend.
Causes for Rejection
Specimen greater than 30 hours old; refrigerated, frozen, clotted, or transferred specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 30 hours |
| Refrigerated | Unacceptable |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant