Mitogen‑induced Lymphocyte Proliferation Panel (PHA, Con A, PWM)
Also known as: Antigen-induced Cell Proliferation, Candida, mitogen/antigen-induced, Tetanus Toxoid, mitogen/antigen-induced
Use
This test evaluates the capacity of a patient’s T and B lymphocytes to respond to mitogenic stimulation using three mitogens: phytohemagglutinin (PHA) and concanavalin A (Con A), which preferentially stimulate T-cell proliferation, and pokeweed mitogen (PWM), which preferentially stimulates B-cell proliferation. It is used to assess immune function and responsiveness in clinical settings where immune competence is being evaluated.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Cell-based / Cytometry
Biomarkers
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
5 mL
Container
sodium heparin (green‑top) tube
Collection Instructions
Whole blood must be transported at room temperature and delivered to the testing laboratory within 48 hours after collection. Maintain and transport blood at room temperature. Avoid temperatures 37° C.