Lymphoma (Aggressive) Panel by FISH
Also known as: FISH ALYMP
Use
This test aids in the diagnosis of aggressive large B-cell lymphoma with features intermediate between Burkitt lymphoma and diffuse large B-cell lymphoma (DLBCL) and is used to confirm suspected double-hit lymphoma. It is designed to identify double hit and triple hit lymphomas, which are aggressive lymphomas characterized by a poor survival rate with intermediate morphological features between diffuse large B-Cell lymphoma and Burkitt lymphoma.
Special Instructions
Not provided.
Limitations
The test uses Fluorescence in situ Hybridization (FISH) and may not identify all potential rearrangement partners. Frozen, clotted, or paraffin-embedded specimens are unacceptable for testing. Interpretation may be compromised if clinical indications or specimen type are not provided with the test order. This test has not been cleared or approved by the US Food and Drug Administration; it is developed by ARUP Laboratories, a CLIA-certified laboratory, intended for clinical purposes.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
3 mL
Minimum Volume
1 mL
Container
Green (sodium heparin) tube
Collection Instructions
Collect nondiluted bone marrow in a heparinized syringe. Transfer 3 mL bone marrow to a green (sodium heparin) tube.
Storage Instructions
Room temperature
Causes for Rejection
Frozen specimens, paraffin-embedded specimens, clotted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 48 hours |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant