Ph-Like Acute Lymphoblastic Leukemia (ALL) Panel by FISH
Also known as: F PHLK ALL
Use
This test is recommended for individuals suspected of having Ph-like Acute Lymphoblastic Leukemia (ALL). It uses fluorescence in situ hybridization (FISH) methodology to detect specific genetic rearrangements associated with the disease. These rearrangements can help in diagnosing Ph-like ALL, which is characterized by a prognostic factor indicating a poor response to traditional therapies and identifies patients who may benefit from targeted therapies.
Special Instructions
Not provided.
Limitations
The test might provide compromised or delayed results if adequate clinical indication or specimen type information is not provided with the test order. Furthermore, paraffin-embedded specimens and clotted specimens are unacceptable, which could lead to sample rejection. The test was developed by ARUP Laboratories and is not cleared or approved by the FDA but is performed in a CLIA-certified lab for clinical purposes.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
3 mL
Minimum Volume
1 mL
Container
green (sodium heparin) tube
Collection Instructions
Nondiluted bone marrow aspirate collected in a heparinized syringe.
Storage Instructions
Room temperature.
Causes for Rejection
Paraffin-embedded specimens. Clotted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 48 hours |
| Frozen | Unacceptable |
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